Florence Products > Florence eBinders

Digital Clinical Trial Site Workflows for Electronic Investigator Site Files, Electronic Participant Binders and Electronic Logs.

Digitize all of your study binder workflows with Florence eBinders™ and provide remote access for start-up, monitoring and source data review for your sponsors. eBinders is trusted by 10,000 research sites around the globe.

Why Sites Choose Florence eBinders

Go Digital from Start-up to Close-out

Create, edit, distribute, collect, sign and review all investigator site files, electronic logs and participant binders electronically within a single platform. Speed study start-up by as much as 40%. One NCI Cancer Center reduced average time to sign from 2 weeks to 4 hours.

Experience Flexible Workflows

Every site is unique and has custom workflows and standard operating procedures. Florence eBinders lets you set up your structures and workflows the way you need while maintaining regulatory compliance. Empower remote workforces to help your team work from anywhere.

Enjoy an Easy-to-use Interface

Florence is rated the #1 clinical trial workflow platform on G2 for ease of use, ease of setup, and customer support. Even the most paper-loving PI will enjoy moving to Florence eBinders – and our industry-leading implementation and customer operations team will help you do it!

Use Electronic Participant Binders

Our front-end integration with your EMR/EHR provides seamless source binder document collection, redaction, and storage. Provide monitors with secure remote access to source data for review and verification in a single platform.

Automate Compliance

Built-in compliance features include automated audit trails, version control, extensive user permission options and in-app redaction. Plus, your team is supported by our extensive compliance program to help develop SOPs for going digital.

Manage Multiple Site Locations

Easily manage document collaboration across multiple locations in a single platform. Enable a fully remote team with virtual workflows, signatures and task management.

Enable Remote Monitoring

Give sponsor and CRO monitors secure and compliant access to your electronic investigator site file and redacted participant binder. Automate scheduling of remote visits, track monitor activity, and communicate with your monitor on follow-up items.

Gain Site-wide Visibility

Global dashboards and project milestones offer a single view of all your studies. Track expired documents, missing signatures, and outstanding tasks in one central location.

Customizable Electronic Logs

Improve patient safety, increase study speed, and ensure data quality with electronic clinical trial logs on Florence. Customize workflows for any log you need – Delegation of Authority Logs, Adverse Event Logs, Training Attestation Logs, Informed Consent Version Logs, Screening/Enrollment Logs, and more.

In clinical research, compliance is crucial. We’ve got you covered.

FDA Part 11 Compliance Logo
HIPAA Compliance Logo
ICH GCP Complaint Logo
GDPR Compliant Logo
EU Annex 11 Compliant Logo
EU-US Privacy Shield Compliant Logo

According to user reviews, Florence is rated the #1 clinical trial workflows platform for ease-of-setup, ease-of-use and customer support.

Why being rated #1 out of 190 clinical trial platforms on G2, the peer-to-peer review site, matters for you.

  • High Adoption: We lead the industry with 92%+ site technology activation per study.

  • Faster Timelines: Intuitive workflows that eliminate duplicate work mean work gets done fast.

  • Low FTE Burden: You don’t need large dedicated IT teams to support implementation and management.

  • Always Reliable: Our customers have had 100% uptime over the last 12 months. We’re there when you need us.

Dr. Christina Brennan Headshot
Blue Quote Box

Collaborating in real-time on a single document management platform helps us tackle study tasks faster and keep research on track.

Dr. Christina Brennan
VP of Clinical Research

We are committed to making you and your sites successful.

Site Adoption Rate
Uptime Past 12 Months
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Overview of Florence eBinders

Accelerate Study Start-up

Use intuitive workflows to get your study set up and activated fast.

  • Control and standardize eISF templates and naming conventions based on your workflows and SOPs for a quick setup.

  • Customize granular access and permissions for your entire study team and external users (regulatory agencies, CROs, sponsors, other sites, etc.).

  • Create placeholders, due dates and task assignments to keep studies progressing.

  • Create, distribute and complete customizable electronic logs.

  • Integrate eBinders with your CTMS to reduce duplicate study start-up workflows.

Sync Source with Participant Binders

Create electronic participant binders to collect all participant source data in a single location.

  • Use the front-end integration with any EMR/EHR system to route certified copies to participant binders.

  • Built-in redaction controls ensure only authorized users see PHI.

  • Grant remote participant binder access to monitors for source data verification and review.

Track Study Performance in Real-Time

Keep track of your entire study and identify risk areas with advanced reports and dashboards.

  • Run reports around document health metrics, open action items, study attributes and ISF completeness.

  • Track study milestones through custom dashboards and reports.

  • Create, assign and complete document tasks directly in the platform.

Remote Monitoring with Florence eBinders for eRegulatory, eSource, and eISF

Enable Remote Monitoring

Equip your site to work with sponsors remotely on start-up, monitoring and source data review.

  • Eliminate duplicate work uploading documents into sponsor portals or vaults by giving sponsors direct access.

  • Provide secure access to redacted participant binders for source data review.

  • Collaborate with monitors on workflows with quality control and communications modules.

Digitize Study Logs

Migrate all of your study logs into a digital format for creation, completion and review.

  • Create a digital log for any of your existing log workflows (DOA, AE, Training, Financial Disclosure, Screening/Enrollment).

  • Route logs for compliant eSignatures with built-in audit trails and access controls.

  • Users can complete and eSign logs anywhere, anytime.

Remote Monitoring with Florence eBinders for eRegulatory, eSource, and eISF

“The regulatory team is very happy with the process. It gives me great pleasure to have partnered with Florence to help them be more efficient with tasks.”

Director, Research Quality and Regulatory Compliance
Multi-Site Health System

“We have staff in several different locations, so having a central access point for our information was very important and a huge draw.”

Associate Director of Research Administration
Academic Cancer Center

“We manage multi-center studies, and eBinders gives us the power to be several places at once.”

Director of Clinical Research Administration
Site Network

Core Florence eBinders Capabilities

  • 21 CFR Part-11 Compliant (Learn More)

  • Complete Online Document Management

  • Fully Compliant eSignatures

  • Remote Access for Sites, Monitors, and Auditors

  • Secure Permission-based Access Control

  • Flexible and Custom Binder Structures

  • Robust Project Management

  • Automated Filing of Centralized Documents into eBinders

  • CTMS Integration

  • EMR Integration

  • Outlook Email Integration

  • Secure and Compliant Audit Trails

  • Rated the Easiest-to-use Solution

  • Clinical-Trial-Experienced Implementation and Support Team

  • Dashboard for Tracking Key Metrics

  • Unlimited Document Storage

  • Documents Linked to Single Source for Easy Version Updating

  • Long-term Archived Storage of All Documents and Structures

  • One-click eISF Study Download

  • Highest Security Cloud Storage

  • Secure Access from Any Device

  • Extensive Training for Your Team

  • Detailed Library of Support and Training Documents

  • Custom SOP Development

Florence Supports Site Enablement on a Global Scale

Florence now supports workflows between sponsors and more than 10,000 study sites in 45 countries.

Learn about how to streamline your workflows with Florence eBinders.