Florence’s eBinders™

Digitize, automate, and integrate your investigator site files, participant binders, and logs – while providing remote monitoring for sponsors and CROs.

Other tools promise to meet your needs, but they are primarily built to support sponsor workflows.

Site First

They build solutions for sponsors…but you need something built for sites.

Flexibility

They force you into workflows…but you need it to be adaptable to your specific needs.

Integration

They lock you into their environment…but you need full integration with your existing systems.

Go Digital from Start-up to Close-out

See how it works

Regulatory Workflows

Transition from paper-based ISFs to a site-controlled, web-based system for effortless creation, management, and sharing of essential regulatory documents.

  • Role Based Access

  • Version Control

  • Audit Trails

  • Part 11 & Annex 11 eSignatures

  • Digital Logs

  • Long-term Archiving

System Administration

Leverage intuitive workflows for rapid study setup and activation, enabling effortless digital multi-site study management.

  • Control and standardize eISF templates and naming conventions based on your workflows and SOPs

  • Customize granular access and permissions for your entire study team and external users

  • Create placeholders, due dates and task assignments to keep studies progressing

  • Identify risk areas with advanced reporting and dashboards

Source Management

Sync source with participant binders to collect all participant source data in a single location.

  • Integrate with your CTMS and EMR/EHR system to route certified copies to participant binders

  • Built-in redaction controls ensure only authorized users see Protected Health Information (PHI)

  • Florence ePrinter enables secure, encrypted digital exchange of sensitive documents between clinical systems

Remote Monitoring

Work with sponsors and CROs remotely on start-up, monitoring and source data review.

  • Empower monitors to review eISF content before on-site visits, ensuring smoother collaboration and preparation

  • Eliminate duplicate document uploads to sponsor portals with direct access to redacted participant binders

  • Automate remote visit scheduling, monitor activity tracking, and follow-up communication

Real success, real stories

“We love the ability to set up regulatory files just like we would in paper format. Importing is so easy, as is sending out requests for signatures.”

– Mark Sulik, PharmD CCRP, Director of Clinical Research

  • 20-30+ hours saved per week

  • Smooth transition from paper to digital workflows

  • Faster document circulation and signatory capture

  • Reduced signature wait time from over a week to under an hour

  • Accelerated staff onboarding from weeks to days

  • Supports 1,200+ MCW and affiliate users, plus 1,000+ external monitors

  • Enhanced document organization and standardized processes, improving efficiency and reducing duplication across multiple studies

“Operationally, digital collaboration brings about so much improvement it is well worth every dollar that you invest in it.”

– Chad Adams, Associate Director of Research Administration

  • 100% elimination of paper shadow-charts and binder rooms

  • eCRF workflows across reg and clinical teams

  • ePrinter capturing all source data from EMR

Florence is used to support over 7.2 million monitoring workflows per month across 20k sites in 90+ countries.

  • 30 studies onboarded the first week

  • 150+ PIs trained on eSignatures

  • 10,000 eSignatures in the first 6 months

  • OnCore CTMS Integration

  • 41.8% reduction in document cycle time

  • 49.2% acceleration in study startup

  • 12.5% increase in study capacity

  • 6,500 monthly document signatures

  • 580,000+ documents managed in Florence

Integrate with the tools you use every day.

Drive results that matter

Mitigate Risk

Stay inspection-ready with automated audit trails, version control, user permissions, and secure in-app redaction.

Accelerate Timelines

Cut study start-up times by up to 40% and reduce study close-out by two weeks with effortless workflow streamlining.

Increase Capacity

Save 20-30 hours weekly, allowing more focus on patient care and less on administrative tasks.

In clinical research, compliance is crucial. We’ve got you covered globally.

Improve Your Operational Efficiency