Florence Workflows > Remote Monitoring

Remotely Monitor Study Sites by Deploying and Connecting to Electronic Investigator Site Files

Activate remote monitoring for your studies by connecting to the industry-standard electronic Investigator Site File (eISF), Florence eBinders.

Remote Monitoring with Florence

Florence facilitates 3 million remote monitoring workflows
every month across 10,000 study sites in 45 countries.

Why Clinical Operations Teams Choose Florence for Remote Monitoring

Work on a Global Scale

Florence supports more than 3 million remote monitoring events per month across 10,000 study sites in 45 countries. Whether you need to conduct one study at 10 sites or a thousand at 10,000 sites, we can help. Plus we are compliant on a global scale.

Experience Sites’ Trust in Florence

When you deploy remote monitoring through the Florence eBinders Electronic Investigator Site File you can expect the industries highest adoption rate. That’s because sites rate us #1 for ease-of-use, ease of setup and support. We average 92%+ full site adoption rates.

Maximize CRA Efficiency

Connecting Florence eTMF to Florence remote site access allows CRAs to monitor over 60 sites a week with our system. CRA staffing bottlenecks are reduced, travel costs are reduced, and CRAs can make a greater impact on the study sites.

Accelerate Study Timelines

Deploying a complete Electronic Investigator Site File to your study sites means they do all their administrative work in one place on a compliant workflow platform. Top sites reduce start-up by more than 40%.

Improve eTMF Quality

Over 80% of your eTMF is generated at the trial site. By integrating our platform with your existing eTMF or with the Florence eTMF, you can exchange documents seamlessly. The eTMF pass rate of one customer increased from 65% to 98.7%.

Gain 24/7 Visibility Across All Sites

Advanced dashboards and reports give you 24/7 visibility into site progress, document status and outstanding tasks. Know what’s going on at your sites at all times.

Blue Quote Box

Florence’s platform is helping us to respond to the changing environment due to COVID-19 and further progress COVID-19 research with the capability to perform remote monitoring where approved by regulatory authorities and ethics committees.

Rob Goodwin
VP and Head of Operations in Global Product Development

In clinical research, compliance is crucial. We’ve got you covered.

FDA Part 11 Compliance Logo
HIPAA Compliance Logo
ICH GCP Complaint Logo
GDPR Compliant Logo
EU Annex 11 Compliant Logo
EU-US Privacy Shield Compliant Logo

Remote Site Monitoring Workflows with Florence

Start-up Sites Remotely

Remotely activate and start-up your study sites with a complete suite of electronic binder solutions.

  • Deploy the industry-standard electronic Investigator Site File (eISF) to every site with templates and pre-built workflows.

  • Distribute fully electronic Participant Binders to study sites.

  • Create and track placeholders, due dates and task assignments to keep studies progressing.

  • Learn more about our entire remote site start-up workflow.

24/7 Continuous Monitoring of Sites

Access your study sites’ Electronic Investigator Site Files anytime for continuous monitoring.

  • Perform remote monitoring from anywhere across your portfolio of study sites.

  • Help study sites minimize disruptions when they do their work from start to finish in the platform.

  • Support risk-based monitoring plans with easy access to every document.

Communicate and Collaborate with Sites Remotely

Assign tasks and send compliant communications directly in the sites’ eISF workflows.

  • Create and assign document tasks to teams or individuals through the platform.

  • Electronically distribute communications, protocol amendments and other critical documents to all sites at once.

  • Mitigate problems faster with advanced insights into risk areas or underperforming sites.

Quality Control and Sync Documents to eTMF

Eliminate the need for mailing, emailing, and faxing study documents and for legacy site upload portals by directly integrating your eTMF with your sites’ eISFs.

  • Built-in quality control workflows to review, approve or reject with action plan documents from sites.

  • Sync final site documents directly into your eTMF for more timely and complete trial master files.

  • Create document queries and communicate with your sites through the monitor review module.

“Our highest performing CRAs are now “visiting” 64 sites per week with remote monitoring on Florence, up from 2 per week.”

VP Clin Ops, Top 3 Global CRO

92% of 140 study sites in 8 countries were activated on Florence for remote source access and monitoring in four weeks.”

VP Clin Ops, Top 3 Pharma

“Our eTMF QA score went from a 65% submission pass rate to 98.7% by having real-time remote access to the site eISF.”

Aperio Clinical Outcomes

Florence’s SiteLink
Remote, Always-On Research Workflows with Your Study Sites

Activate remote site start-up, monitoring, and source data review/verification on SiteLink. Connect and deploy Florence eBinders™, the industry-standard electronic Investigator Site File and Electronic Participant Binder, on a global scale to every site in your study.

  • Remote Site Start-up

  • Remote Site Monitoring

  • Remote Site SDV and SDR

  • Remote Site Management

Remote Monitoring with Florence

According to user reviews, Florence is rated the #1 clinical trial workflows platform for ease-of-setup, ease-of-use and customer support.

Why being rated #1 out of 190 clinical trial platforms on G2, the peer-to-peer review site, matters for you.

  • High Adoption: We lead the industry with 92%+ site technology activation per study.

  • Faster Timelines: Intuitive workflows that eliminate duplicate work mean work gets done fast.

  • Low FTE Burden: You don’t need large dedicated IT teams to support implementation and management.

  • Always Reliable: Our customers have had 100% uptime over the last 12 months. We’re there when you need us.

We are committed to making you and your sites successful.

Site Adoption Rate
Uptime Past 12 Months
Avg. Support Response Time

Florence Supports Site Enablement on a Global Scale

Florence now supports workflows between sponsors and more than 10,000 study sites in 45 countries.

Dr. Christina Brennan Headshot
Blue Quote Box

We love working with Sponsors on Florence. Collaborating in real-time on a single document management platform helps us tackle study tasks faster and keep research on track.

Dr. Christina Brennan
VP of Clinical Research

Learn more about activating always-on, remote workflows with sites.